Key result
Depressive symptoms affect ~27% of PVC patients, linked to PVC count, female sex, and age.
Why the study?
Prevalence and risk factors of depressive symptoms in Chinese patients with premature ventricular contractions without structural heart disease were not well characterized.
Cross-Sectional (n=1,144)
Depressive symptoms are highly prevalent (27%) in Chinese patients with PVCs without structural heart disease, and are independently associated with female sex, age, education, settlement type, and PVC burden.
Answers are grounded in this paper and cite their sources.
Depressive symptoms may correlate with PVCs without SHD; leaves open whether screening or treatment alters outcomes.
HYPOTHESIS: Our objective was to study depressive symptoms and potential risk factors in Chinese persons with premature ventricular contractions (PVCs) without structural heart disease. METHODS: The Zung self-rating depression scale (ZSDS) was used to assess depressive symptoms. Correlations between depressive symptoms and sociodemographic and medical factors were analyzed by logistic regression. BACKGROUND: Prevalence of depressive symptoms in coronary heart disease (CHD) is higher that in the general population and those for the majority of other chronic symptoms in patients with premature ventricular contractions (PUCS). RESULTS: Of 1,144 patients with PVCs (488 males, 656 females), age 51 +/- 23 years, disease duration 1 mo - 23 y, a total of 309 (27%) patients were categorized as having depressive symptoms. Depressive symptoms increased with age, income, education level, nationality, PVC count/24h, society support, and settlement type (p < 0.05). Univariate logistic regression showed that being female, level of education, age, settlement type, and PVC count/24h significantly correlated with depressive symptoms (p < 0.05). Multivariate logistic regression indicated that 5 variables-female sex, education level, settlement type, age, and PVC count/24h significantly and independently related with depressive symptoms (p < 0.05). CONCLUSIONS: In the Chinese population, depressive symptoms in subjects with PVCs were frequent. The village settlement type, female sex, age, PVC count/24h, and education level were independent risk factors for depressive symptoms. Further research on the relationship between PVCs and depressive symptoms in China is necessary.
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Liang et al. (2009) conducted a cross-sectional in Premature ventricular contractions without structural heart disease (n=1,144). Risk factors (female sex, age, PVC count, education, settlement type) was evaluated on Depressive symptoms (p=<0.05). Female sex, age, PVC count, education level, and village settlement type were independent risk factors for depressive symptoms, which were present in 27% of Chinese patients with PVCs.
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