An Interaction Effect Analysis of Thermodilution-Guided Hemodynamic Optimization, Patient Condition, and Mortality after Successful Cardiopulmonary Resuscitation

Figures

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  Figure 1. The selection of study population and eligibility of patients. A total of 254 patients after successful cardiopulmonary resuscitation were screened, and 63 were included into the study based on the inclusion and exclusion criteria. N: number of patients; PiCCO™: pulse index contour cardiac output.

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  Figure 2. (A). Hemodynamic management of patients in PiCCO™ group in the case of low (<3 L/min/m2) cardiac index. (B). Hemodynamic management of patients in PiCCO™ group in the case of normal or high (>3 L/min/m2) cardiac index. SVRI: systemic vascular resistance index.

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  Figure 3. Cumulative incidence of 30 day and 1 year mortality by PiCCO status. Kaplan–Meier curves and log-rank tests were performed. p: level of significance; and PiCCO: pulse index contour cardiac output.

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  Figure 4. Comparison of PiCCO use, 30 day mortality, and 1 year mortality by patient condition characteristics. Chi-square test was performed. ∗: p < 0.05; #: p < 0.2; PiCCO: pulse index contour cardiac output; IABP: intra-aortic balloon pump; PCI: percutaneous coronary intervention; and STEMI: ST-elevation myocardial infarction.

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  Figure 5. Interaction effects between PiCCO™-application, 30 day mortality, and patient condition characteristics. Patient conditions are depicted in the different subfigures; (a) hyperlipidemia; (b) STEMI at admission; (c): PCI treatment; (d): cardiogenic shock at admission; (e): IABP insertion; (f): catecholamine administration; (g): stroke in the prior history. Crude and adjusted logistic regressions were performed. In the crude models, all the interaction term dummy variables were included as separate variables. In the adjusted models, non-significant dummies were combined. ∗: p < 0.05; #: p < 0.2; catechol: catecholamine; CS: cardiogenic shock; HLP: hyperlipidemia; IABP: intra-aortic balloon pump; N: number of patients; PCI: percutaneous coronary intervention; PiCCO: pulse index contour cardiac output; and STEMI: ST-elevation myocardial infarction.

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  Figure 6. Interaction effects between PiCCO™-application, 1 year mortality, and patient condition characteristics. Patient conditions are depicted in the different subfigures; (a) hyperlipidemia; (b) STEMI at admission; (c): PCI treatment; (d): cardiogenic shock at admission; (e): IABP insertion; (f): catecholamine administration; (g): stroke in the prior history. Crude and adjusted logistic regressions were performed. In the crude models, all the interaction term dummy variables were included as separate variables. In the adjusted models, non-significant dummies were combined. ∗: p < 0.05; #: p < 0.2; catechol: catecholamine; CS: cardiogenic shock; HLP: hyperlipidemia; IABP: intra-aortic balloon pump; N: number of patients; PCI: percutaneous coronary intervention; PiCCO: pulse index contour cardiac output; and STEMI: ST-elevation myocardial infarction.