Review reveals persistent challenges in reversing airway structural remodelling in asthma, highlighting the need to target airway smooth muscle.
Extract Asthma is a chronic, heterogeneous respiratory disease affecting >260 million people worldwide [1]. It is characterised by a complex interplay of airway hyperresponsiveness, inflammation and structural remodelling [2, 3]. While current pharmacological interventions can effectively mitigate inflammation and bronchoconstriction in people living with asthma, reversing or preventing airway remodelling remains a significant clinical challenge.
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Reza et al. (2026) studied this question.
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