Key result
Lower GFR correlates moderately with LV systolic dysfunction in male chronic heart failure patients.
Why the study?
The increasing prevalence of chronic cardiovascular disease and associated states motivates evaluation of kidney filtration function in patients with chronic heart failure.
Cross-Sectional (n=70)
No
In male patients with chronic heart failure due to coronary heart disease and hypertension, glomerular filtration rate correlates significantly with the degree of left ventricular systolic dysfunction, highlighting the presence of cardiorenal syndrome.
Answers are grounded in this paper and cite their sources.
GFR-LV dysfunction correlation in male HF patients supports cardiorenal monitoring; leaves open whether it alters outcomes.
Aim. The relevance of the chosen research direction is stipulated by increasing prevalence of chronic cardiovascular disease and states associated with it.Methods and results. In order to evaluate the filtration function of the kidneys in patients with CHF there were examined 40 male patients with a verified disorder of left ventricular systolic function, occurred at a background of coronary heart disease and hypertension and 30 healthy individuals of the same age with determination of glomerular filtration rate (GFR) by endogenous creatinine clearance. It is shown that in patients with impaired left ventricular systolic function in the background of coronary heart disease and hypertension the chronic kidney disease is manifested. The concentration of creatinine in patients ranged reference values 85,2 ±0,4 mmol / l, and the glomerular filtration rate is closely correlated (r=0,60) with the degree of violation of left ventricular systolic function. Conclusion. This indicates the formation of cardiorenal syndrome encumbrance and mutual pathologies of the cardiovascular system and chronic kidney disease.
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Kovalevskaya et al. (2015) conducted a cross-sectional in Chronic heart failure and cardiorenal syndrome (n=70). Impaired left ventricular systolic function (chronic heart failure) vs. Healthy individuals of the same age was evaluated on Correlation between glomerular filtration rate and the degree of left ventricular systolic function impairment (r=0.60). In male patients with chronic heart failure, the glomerular filtration rate closely correlated (r=0.60) with the degree of left ventricular systolic function impairment, indicating the formation of cardiorenal syndrome.
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