Key result
Preoperative mechanical bowel preparation with polyethylene glycol did not significantly reduce postoperative complications compared to cleansing enemas in patients with right-sided colon cancer (9.8% vs 6.7%, p>0.05).
Why the study?
Does preoperative mechanical bowel preparation with PEG improve immediate surgical outcomes in patients with right-sided colon cancer?
Cohort (n=349)
No
Does preoperative mechanical bowel preparation with PEG improve immediate surgical outcomes in patients with right-sided colon cancer?
Absolute Event Rate: 9.8% vs 6.7%
p-value: p=>0.05
Preoperative mechanical bowel preparation with PEG does not enhance immediate surgical outcomes in right-sided colon cancer patients.
No benefit of PEG over enemas seen; leaves open optimal bowel prep in right-sided colon cancer surgery.
Objective: to analyze literature data on the effectiveness of preoperative mechanical bowel preparation (MBP), and on the basis of our own data to perform a comparative analysis of immediate MBP results in patients operated on right-sided colon cancer. Materials and methods. We reviewed literature data relevant to the use of MBP and performed a retrospective analysis of the immediate results of surgical interventions on right-sided colon cancer in 349 patients having undergone MBP with polyethylene glycol (PEG) compounds (n = 186) and without the use of PEG (n = 163). Results. The incidence rates of complications in the patients of groups I and II were 6.7 % and 9.8 % (P>0.05), anastomotic leak rates were 0.6 % and 1.6 % (P>0.05), postoperative death rates — 1.2 % and 1.6 % (P>0.05), the average durations of the postoperative period were 14.9 and 12.1 days, respectively (P>0.05). Conclusion. The use of preoperative MBP with PEG compounds does not result in enhancing the immediate results of the surgical treatment of patients with right-sided cancer.
No takes yet. Share an insight, caveat, or question.
Dyatlov et al. (2021) conducted a cohort in Right-sided colon cancer (n=349). Mechanical bowel preparation with polyethylene glycol (PEG) vs. Cleansing enemas (without PEG) was evaluated on Incidence of postoperative complications (p=>0.05). Preoperative mechanical bowel preparation with polyethylene glycol did not significantly reduce postoperative complications compared to cleansing enemas in patients with right-sided colon cancer (9.8% vs 6.7%, p>0.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: