Key result
Primary cardiac lymphoma shows potential for early isolated CNS relapse despite complete remission after immunochemotherapy.
Why the study?
Isolated central nervous system relapse in primary cardiac lymphoma is very uncommon and lacks a well-established standard treatment approach.
Population
Two patients with primary cardiac lymphoma diagnosed by endomyocardial biopsy
Comparison
Immunochemotherapy followed by salvage therapy for isolated CNS relapse
Design
Case report
Authors
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May prompt CNS surveillance in primary cardiac lymphoma post-remission; leaves open role of prophylaxis in prospective cohorts.
Case Report (n=2)
No
Isolated CNS relapse is a rare but significant complication in primary cardiac lymphoma, highlighting the potential need for routine baseline CNS evaluation with MRI and lumbar puncture.
Juan Montoro (2014) conducted a case report in Primary cardiac lymphoma (n=2). Immunochemotherapy and CNS-directed salvage therapy was evaluated on Clinical outcome. Two patients with primary cardiac lymphoma developed rare isolated parenchymal central nervous system relapses shortly after achieving complete remission with immunochemotherapy.
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