Key result
Supravalvular aortic stenosis discordance in fraternal twins points to genetic rather than environmental origin.
Why the study?
The aetiological factors of supravalvular aortic stenosis remain unclear, with uncertainty about environmental versus genetic origins.
This case report suggests a genetic rather than environmental etiology for supravalvular aortic stenosis.
Does not alter aortic stenosis management; leaves open genetic etiology of supravalvular disease.
A case of subvalvular aortic stenosis in one of a set of dissimilar twins is reported. The case is discussed in terms of the aetiological factors involved and supports the view that supravalvular aortic stenosis is not environmental and may be genetic in origin.
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NEILSON et al. (1978) studied this question. Supravalvular aortic stenosis observed in only one of a set of dissimilar twins suggests that the condition is genetic rather than environmental in origin.
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