Study of Genetic Resistance to Scrapie in Sheep of the Gene Pool Herd of the Southern Meat Breed and in Their First Generation (F1) Crossbreeds with Katumskaya Breed by the Prion Protein Gene (PRNP)

This is the authors' abstract. We don't add key points for this paper.

Marker-assisted selection has only recently begun to be used in the breeding of the Southern Meat breed, and its resistance to diseases has not been studied before. Currently, the work is underway to create a new selective type within this breed, which differs from representatives of the original forms by a high meat productivity. As an additional selection criterion, the effective breeding work should include the analysis of the prion protein gene (PRNP) polymorphism to determine the classes of genetic resistance to classical and atypical forms of scrapie, which will allow us to increase significantly the genetic resistance to scrapie in new generations of Southern Meat breed sheep. In our study, data on genetic resistance to scrapie was for the first time obtained in sheep of the gene pool herd of the Southern Meat breed and in their descendants, crosses with the Katumskaya breed (1/2) of the first generation (F1).