Key result
PAC use in cardiac surgery shows no mortality benefit but is linked to shorter stays.
Why the study?
The utility of pulmonary artery catheters and their measurements in adult cardiac surgery patients depends on factors including data interpretation and personnel training, and associations with clinical outcomes were unclear.
Does pulmonary artery catheter use improve 30-day in-hospital mortality and morbidity in adult patients undergoing cardiac surgery?
Cohort (n=6,844)
Yes
Does pulmonary artery catheter use improve 30-day in-hospital mortality and morbidity in adult patients undergoing cardiac surgery?
Odds Ratio: 1.17 (95% CI 0.65–2.1)
Absolute Event Rate: 0.7% vs 0.6%
p-value: p=0.516
Pulmonary artery catheter use during adult cardiac surgery may be associated with decreased length of stay and cardiopulmonary morbidity, despite an increase in infectious morbidity.
May reduce length of stay and cardiopulmonary morbidity without mortality benefit; leaves open net value pending randomized trials.
BACKGROUND: The utility of pulmonary artery catheters (PACs) and their measurements depend on a variety of factors including data interpretation and personnel training. This US multi-center, retrospective electronic health record (EHR) database analysis was performed to identify associations between PAC use in adult cardiac surgeries and effects on subsequent clinical outcomes. METHODS: This cohort analysis utilized the Cerner Health Facts database to examine patients undergoing isolated coronary artery bypass graft (CABG), isolated valve surgery, aortic surgery, other complex non-valvular and multi-cardiac procedures, and/or heart transplant from January 1, 2011, to June 30, 2015. A total of 6844 adults in two cohorts, each with 3422 patients who underwent a qualifying cardiac procedure with or without the use of a PAC for monitoring purposes, were included. Patients were matched 1:1 using a propensity score based upon the date and type of surgery, hospital demographics, modified European System for Cardiac Operative Risk Evaluation (EuroSCORE II), and patient characteristics. Primary outcomes of 30-day in-hospital mortality, length of stay, cardiopulmonary morbidity, and infectious morbidity were analyzed after risk adjustment for acute physiology score. RESULTS: < 0.001). CONCLUSIONS: Use of a PAC during adult cardiac surgery is associated with decreased length of stay, reduced cardiopulmonary morbidity, and increased infectious morbidity but no increase in the 30-day in-hospital mortality. This suggests an overall potential benefit associated with PAC-based monitoring in this population. TRIAL REGISTRATION: The study was registered at clinicaltrials.gov (NCT02964026) on November 15, 2016.
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Shaw et al. (2018) conducted a cohort in Cardiac surgery (n=6,844). Pulmonary artery catheter (PAC) monitoring vs. No pulmonary artery catheter was evaluated on 30-day in-hospital mortality (OR 1.17, 95% CI 0.65-2.10, p=0.516). Use of a pulmonary artery catheter during adult cardiac surgery was not associated with a significant difference in 30-day in-hospital mortality (OR 1.17) but was associated with decreased length of stay and cardiopulmonary morbidity.
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