Key result
Paroxetine use during electroconvulsive therapy resulted in a mean seizure length approximately twice that of controls taking tricyclic antidepressants.
Why the study?
Does paroxetine affect seizure length during electroconvulsive therapy in inpatients compared to tricyclic antidepressants?
Does paroxetine affect seizure length during electroconvulsive therapy in inpatients compared to tricyclic antidepressants?
Paroxetine is associated with approximately doubled seizure length during electroconvulsive therapy compared to tricyclic antidepressants.
Answers are grounded in this paper and cite their sources.
May warrant seizure monitoring with paroxetine in ECT; Level 5 data leaves open confirmation versus TCAs.
This study reports the effect of paroxetine, a selective serotonin reuptake inhibitor, on seizure length during electroconvulsive therapy. Seven inpatients taking paroxetine were compared with 7 controls taking tricyclic antidepressants. The mean seizure length of the paroxetine group was approximately twice that of the control group.
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Stephen M. Curran (1995) studied this question. Paroxetine use during electroconvulsive therapy resulted in a mean seizure length approximately twice that of controls taking tricyclic antidepressants.
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