Predictors of permanent pacemaker implantation after ACURATE neo transcatheter heart valve implantation
Key result
ACURATE neo TAVI yields a ~10% PPI rate, driven by conduction baseline and implant depth.
- n=1,000
Why the study?
Rates of permanent pacemaker implantation using the ACURATE neo device have been low, but data on risk factors for PPI with this device are scarce.
What are the predictors of permanent pacemaker implantation in patients with severe aortic stenosis undergoing TAVI with the ACURATE neo device?
Comparison
Patients with and without permanent pacemaker implantation after ACURATE neo TAVI
Design
Single-center cohort study
Authors
Discussion
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Implication
Preexisting AV block or RBBB flags higher PPI risk after ACURATE neo TAVI; leaves open whether optimized implantation depth reduces rates in prospective studies.
Study Design
Type
Cohort (n=1,000)
Multicenter
No
Structured PICO
What are the predictors of permanent pacemaker implantation in patients with severe aortic stenosis undergoing TAVI with the ACURATE neo device?
P
Population
1,000 patients with severe aortic stenosis undergoing transfemoral TAVI using the ACURATE neo prosthesis, excluding those with prior pacemakers or high-grade AV block.
E
Exposure
Transfemoral transcatheter aortic valve implantation (TAVI) using the ACURATE neo prosthesis
O
Outcome
Permanent pacemaker implantation (PPI)safety
Preexisting right bundle branch block, first-degree AV block, and low implantation depth are independent predictors of permanent pacemaker implantation after TAVI with the ACURATE neo device, suggesting that avoiding low implantation depth may reduce this complication.
Cite This Study
Kim et al. (2020) conducted a cohort in Severe aortic stenosis (n=1,000). TAVI using ACURATE neo prosthesis was evaluated on Permanent pacemaker implantation (PPI). Following TAVI using the ACURATE neo device, the permanent pacemaker implantation rate was 10%, with preexisting RBBB, AV block I°, and low implantation depth acting as independent predictors.