Key result
Indian mitral annular dimensions run lower than standard values, risking patient-prosthesis mismatch.
Why the study?
The mitral valve annular dimensions in relation to body surface area in the Indian population were not compared with standard values, which may impact mitral valve replacement outcomes.
How do mitral valve annular dimensions in the Indian population compare to standard values in relation to body surface area?
Cross-Sectional (n=406)
How do mitral valve annular dimensions in the Indian population compare to standard values in relation to body surface area?
Mitral valve annular dimensions in the Indian population are lower than standard values for a given body surface area, highlighting a potential risk for patient-prosthesis mismatch during mitral valve replacement.
May warrant smaller mitral prostheses in Indian patients to reduce mismatch risk; hypothesis-generating data leaves open need for ethnicity-specific validation.
OBJECTIVE: We compare the mitral valve annular dimension in relation to the body surface area of the Indian population as against the standard values. METHODS: The study was conducted between September 2004 and February 2006 on 406 subjects, out of which 252 were males and 154 were females. A spatially oriented B-mode scan echocardiogram was used, with the long-axis plane running parallel to the heart or the left ventricle, the short-axis plane being perpendicular to the long axis, and the four-chamber plane orthogonal to the other two and somewhat representing a frontal plane. Mitral valvular dimensions were recorded in early diastole. RESULTS: The mitral valve showed a steady rise in its diameter with rise in body surface area. For body surface area ranging from 0.61 to 0.7 m², the mitral valve diameter was 15.5mm. There was a sudden increase from 15.5mm to 18 mm for body surface area ranging from 0.71 to 0.8 m². After this sudden increase, the mitral valve diameter steadily increased by 0.2-0.6 mm for every 0.1 m² increase in body surface area. The values obtained from the Indian population were definitely lower than the lower end of standard deviation of the standard values, which are derived in relation to body surface area. CONCLUSIONS: Although the annular dimensions of the mitral valve increased correspondingly with body surface area, they still remained very low in the Indian population as compared with the standard values, which might cause patient-prosthesis mismatch during mitral-valve replacement surgeries.
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Rajendran et al. (2010) reported a cross-sectional. Indian population vs. Standard values was evaluated on Mitral valve annular dimension in relation to body surface area. Mitral valve annular dimensions in the Indian population increased by 0.2-0.6 mm per 0.1 m² BSA but remained lower than standard values, potentially causing patient-prosthesis mismatch.
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