Key result
LA spontaneous echo contrast in chronic AF is linked to persistent AF, hypertension, and LA enlargement.
Why the study?
Left atrial or left atrial appendage spontaneous echo contrast by transesophageal echocardiography requires investigation for clinical risk assessment and treatment guidance in atrial fibrillation patients.
What are the clinical and echocardiographic factors associated with left atrial spontaneous echo contrast in patients with nonvalvular chronic atrial fibrillation?
Observational (n=92)
What are the clinical and echocardiographic factors associated with left atrial spontaneous echo contrast in patients with nonvalvular chronic atrial fibrillation?
Answers are grounded in this paper and cite their sources.
In patients with nonvalvular chronic atrial fibrillation, persistent AF, left atrial enlargement, and hypertension are strongly associated with left atrial spontaneous echo contrast, which can be predicted by CHA2DS2-VASc score and D-dimer levels.
Background: To investigate left atrial or left atrial appendage spontaneous echo by transesophageal echocardiography for clinical risk assessment, providing an important basis for guiding treatment and so on.Methods: Select 113 atrial fibrillation patients who did not have formal warfarin treatment in 2011-2014 and did transesophageal echocardiography, after excluding substandard patients, 92 patients were divided into LASEC positive group (n=63) and negative group (n=29).Analyses the clinical features and echocardiographic parameters.Evaluate the diagnostic value with results of multivariate analysis. Results:The study found a significant difference (P<0.05) between the two groups in the type of AF (permanent AF), hypertension, left atrial diameter, left ventricular diastolic function, among these factors, persistent atrial fibrillation, left atrial diameter >40 mm and hypertension have a extremely significant difference (P<0.01).CHA 2 DS 2 -VASC score, D-dimer in plasma have a predictive value for LASEC patients with atrial fibrillation.Conclusion: Patients with persistent AF have a higher LASEC incidence, LASEC has clinical predictive value, there are certain guiding significance in clinical practice.
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Xu et al. (2015) conducted an observational in Nonvalvular Chronic Atrial Fibrillation (n=92). Left atrial spontaneous echo contrast (LASEC) vs. LASEC negative was evaluated on Clinical features and echocardiographic parameters (type of AF, hypertension, left atrial diameter, left ventricular diastolic function) (p=<0.01). Left atrial spontaneous echo contrast (LASEC) positivity in patients with nonvalvular chronic atrial fibrillation was significantly associated with persistent AF, left atrial diameter >40 mm, and hypertension (P<0.01).
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