Synthesis of regioisomeric cyclopentanones 3-alkyloxy-2-oxabicyclo[3.3.0]octan-6-one (overall yield up to 34%) and 3-alkyloxy-2-oxabicyclo[3.3.0]octan-7-one (overall yield up to 18%) in four steps, starting from enantiomerically pure (–)-(1S,5R)-2-oxabicyclo[3.3.0]oct-6-en-3-one is described.
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Aav et al. (2007) studied this question.
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