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All articles of this category A convenient route to γ-cyano fused pyridine derivatives, which are precursors of NADH models, is described. The method involves the reaction of 3,3-dimethoxy-2-formyl-propionitrile sodium salt ( 1 ) with amino derivatives of electron donating heterocycles leading to the desired products by an easy one-pot synthesis.
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Benoit et al. (1987) studied this question.
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