Answers are grounded in this paper and cite their sources.
Recently developed chemical ligation protocols were elaborated for rapid N-terminal protein PEGylation. We introduce a PEG-salicylaldehyde ester and demonstrate its site-specific ligation to the N-terminus of the RNase S protein and to the therapeutic polypeptide PTH (1-34).
No takes yet. Share an insight, caveat, or question.
Levine et al. (2014) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: