The Impact of the Coinheritance of Alpha Thalassemia and Hemoglobin F Concentration on Sickle Cell Disease

This is the authors' abstract. We don't add key points for this paper.

Alpha thalassemia and hemoglobin F concentration are major modulators of sickle cell disease in many populations. To address the impact of these two modulators on phenotype in sickle cell disease patients from Northern Iraq this study was initiated. Seventy-four Iraqi patients with sickle cell anemia or sickle/β0 thalassemia in steady state were enrolled. They had a median age of 16 years and included 56.8% males. Patients were clinically evaluated and had their blood and reticulocyte count