Identification of New Diterpenoids from Euphorbia calyptrata Cell Cultures

Four new diterpenoids, helioscopinolides F ( 2 ), H ( 4 ), I ( 5 ), and L ( 6 ), were isolated from three different cultured cell lines of Euphorbia calyptrata var. involucrata . Helioscopinolide B ( 1 ) and jolkinolide E ( 3 ), previously found in Euphorbia helioscopia and Euphorbia jolkini, respectively, were also isolated from the same cultures. Structures were identified by spectroscopic methods.