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Diets containing tetracycline antibiotics were fed to hatchery populations of Pacific salmon. Subsequent examination of bone samples from these populations indicates that the tetracyclines are deposited permanently in the skeletal structure, are readily detectable after a period of rapid growth, and do not affect growth or survival. The most satisfactory and consistent marks were obtained by feeding 250 mg of tetracycline antibiotic per kilogram of body weight per day for 4 consecutive days.
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Weber et al. (1967) studied this question.
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