Key result
An electrochemical immunosensor successfully detected antibodies against deamidated gliadin peptides in real serum samples, with results corroborated by a standard ELISA kit.
The developed electrochemical immunosensor provides a promising analytical tool for the clinical diagnosis of celiac disease.
May enable point-of-care celiac serology; leaves open prospective validation before clinical adoption.
The first electrochemical immunosensor (EI) for the detection of antibodies against deamidated gliadin peptides (DGP) is described here. A disposable nanohybrid screen-printed carbon electrode modified with DGP was employed as the transducer's sensing surface. Real serum samples were successfully assayed and the results were corroborated with an ELISA kit. The presented EI is a promising analytical tool for celiac disease diagnosis.
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Neves et al. (2013) studied Celiac disease. Electrochemical immunosensor for deamidated gliadin peptides (DGP) antibodies vs. ELISA kit was evaluated on Detection of antibodies against deamidated gliadin peptides (DGP). An electrochemical immunosensor successfully detected antibodies against deamidated gliadin peptides in real serum samples, with results corroborated by a standard ELISA kit.
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