What question did this study set out to answer?

To assess the efficacy of decellularized dermal grafting as an adjunct to the surgical closure of recurrent oro-nasal fistulas following multiple previous cleft palate repairs.

July 1, 2006Journal of Craniofacial Surgery

The Use of Decellularized Dermal Grafting (AlloDerm) in Persistent Oro-nasal Fistulas after Tertiary Cleft Palate Repair

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To assess the efficacy of decellularized dermal grafting as an adjunct to the surgical closure of recurrent oro-nasal fistulas following multiple previous cleft palate repairs.
Interventional case series of five consecutive patients (N=5) with recurrent post-alveolar oro-nasal fistulas and a history of at least three prior palatal repairs.
Decellularized dermal grafts (AlloDerm) were placed between the nasal mucosa and the levator veli palatini muscle during a von Langenbeck palatal repair.
Patients were evaluated postoperatively over an average follow-up of three months for infection, dehiscence, graft extrusion, and fistula recurrence.
Zero patients experienced recurrence of the oro-nasal fistula or associated symptoms of nasal reflux over an average three-month follow-up.
No instances of graft rejection, infection, or tissue extrusion from the surgical site were observed.

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Implication

Case series demonstrates complete closure of persistent oro-nasal fistulas using decellularized dermal grafts in tertiary cleft palate repairs, indicating viable salvage treatment.

Cite This Study

Cole et al. (2006) studied this question.

synapsesocial.com/papers/6ab34aa1664f6c052eeb164b https://doi.org/10.1097/00001665-200607000-00005

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Implication

Case series demonstrates complete closure of persistent oro-nasal fistulas using decellularized dermal grafts in tertiary cleft palate repairs, indicating viable salvage treatment.

The Use of Decellularized Dermal Grafting (AlloDerm) in Persistent Oro-nasal Fistulas after Tertiary Cleft Palate Repair

Key Points

Discussion

Implication

Cite This Study

The Use of Decellularized Dermal Grafting (AlloDerm) in Persistent Oro-nasal Fistulas after Tertiary Cleft Palate Repair

Key Points

Discussion

Implication

Cite This Study

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