Key result
Intensive blood pressure lowering to less than 120 mm Hg was associated with a 38% relative risk reduction in heart failure compared to standard therapy in the SPRINT trial.
These letters to the editor emphasize the need to consider pleiotropic drug effects and baseline statin use when interpreting the cardiovascular benefits of intensive blood pressure lowering in the SPRINT trial.
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Jonathan Lee Edwards (2016) conducted a letter in Hypertension. Intensive blood pressure lowering vs. Standard goal of < 140 mm Hg was evaluated on Heart failure (38% relative risk reduction, p=.0002). Intensive blood pressure lowering to less than 120 mm Hg was associated with a 38% relative risk reduction in heart failure compared to standard therapy in the SPRINT trial.
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