Key result
Lower preoperative left MCA blood flow velocity is linked to postoperative cognitive decline after cardiac surgery.
Why the study?
The association between preoperative cerebral blood flow velocity and postoperative cognitive decline at three months after cardiac surgery was unclear.
Is reduced preoperative cerebral blood flow velocity associated with postoperative cognitive decline at three months in cardiac surgery patients?
Observational (n=31)
Is reduced preoperative cerebral blood flow velocity associated with postoperative cognitive decline at three months in cardiac surgery patients?
Reduced preoperative cerebral blood flow velocity in the left middle cerebral artery may be an independent risk factor for cognitive decline three months after cardiac surgery.
Preoperative CBF velocity may flag POCD risk after cardiac surgery; this Level 5 observational study leaves open the need for prospective validation.
This extension study investigated the association between preoperative cerebral blood flow (CBF) velocity and postoperative cognitive decline (POCD) at a three-month follow-up in patients who underwent cardiac surgery. Continuous transcranial Doppler ultrasound on both middle cerebral arteries (MCAs) was used preoperatively in 31 right-handed cardiac surgery patients at rest. Each patient performed a neuropsychological evaluation to assess cognitive performance before surgery, at discharge and at three-month follow-up. Patients with POCD at the three-month follow-up had a marginally significantly lower preoperative CBF velocity in the left MCA than patients without POCD. Moreover, the group with POCD had a significantly lower CBF velocity in the left than in the right MCA, whereas no difference between the left and right CBF velocity was found in the group without POCD. These preliminary findings suggest that reduced preoperative CBF velocity in the left MCA may represent an independent risk factor for cognitive decline in patients three months after surgery.
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Benvenuti et al. (2012) conducted an observational in Cardiac surgery (n=31). Reduced preoperative cerebral blood flow velocity vs. Normal preoperative cerebral blood flow velocity was evaluated on Postoperative cognitive decline (POCD) at three-month follow-up. Reduced preoperative cerebral blood flow velocity in the left middle cerebral artery was significantly associated with postoperative cognitive decline at three months in 31 cardiac surgery patients.
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