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April 21, 2026American Journal of Kidney DiseasesOpen Access

The abstract outlines a post-hoc analysis of the VERTIS CV trial assessing the effect of ertugliflozin versus placebo on kidney outcomes after interval cardiovascular events, but reports no results.

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Why the study?

Does ertugliflozin alter the association between interval cardiovascular events and kidney outcomes compared to placebo?

Population

Participants from the VERTIS CV trial (people after and without an interval cardiovascular event)

Comparison

Ertugliflozin vs Placebo

Design

Cohort

Key result

The abstract outlines a post-hoc analysis of the VERTIS CV trial assessing the effect of ertugliflozin versus placebo on kidney outcomes after interval cardiovascular events, but reports no results.

Authors

AOAyodele OdutayoFCFrancesco CosentinoRPRichard E. Pratley

Discussion

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Overview

No results reported on ertugliflozin's kidney effects after interval CV events; leaves open whether SGLT2 inhibition modifies this association.

Study Design

Type

RCT

Structured PICO

Does ertugliflozin alter the association between interval cardiovascular events and kidney outcomes compared to placebo?

P
Population
Participants from the VERTIS CV trial (people after and without an interval cardiovascular event)
I
Intervention
Ertugliflozin
C
Comparator
Placebo
O
Outcome
Kidney outcomes (trajectory of kidney function change after an interval cardiovascular event)

Cite This Study

Odutayo et al. (2026) conducted an RCT in Cardiovascular events and kidney disease. Ertugliflozin vs. Placebo was evaluated on Kidney outcomes after interval cardiovascular events. The abstract outlines a post-hoc analysis of the VERTIS CV trial assessing the effect of ertugliflozin versus placebo on kidney outcomes after interval cardiovascular events, but reports no results.

synapsesocial.com/papers/6ab361a2b76ae2ddf6debbb4https://doi.org/10.1053/j.ajkd.2026.01.017
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