Key result
Persistent lupus activity and glucocorticoid use link to irreversible organ damage in ~50% of patients.
Why the study?
Despite accelerated innovation, there remains a critical need beyond symptom management to address the underlying cause of systemic lupus erythematosus and achieve clinical remission while minimizing steroid-associated organ damage.
Design
Expert discussion
Authors
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Remission is now considered a realistic and necessary goal in SLE management to prevent irreversible organ damage and improve patient outcomes.
Remission is now considered a realistic and necessary goal in SLE management to prevent irreversible organ damage and improve patient outcomes.
Eleanor Roberts (2024) conducted a review in Systemic lupus erythematosus. Long-term oral glucocorticoid use, disease flares, and persistent disease activity lead to irreversible organ damage in 50% of patients with systemic lupus erythematosus within 5 years of diagnosis.
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