Key result
Percutaneous PFO closure completely resolves platypnea-orthodeoxia syndrome following complicated cholecystectomy.
Why the study?
Platypnea-orthodeoxia syndrome is an uncommon diagnosis that can be overlooked in postoperative patients with unexplained arterial desaturation and no evidence of pulmonary embolism.
Case Report (n=1)
Highlights platypnea-orthodeoxia syndrome due to PFO as a rare but treatable cause of unexplained hypoxemia following abdominal surgery.
A 65-year-old woman with no significant prior medical history presented, in the postoperative course of a complicated cholecystectomy, several episodes of arterial desaturation. Pulmonary embolism was repeatedly suspected, but there was no evidence of pulmonary thrombus on the chest computed tomography angiographies obtained. As these episodes were mainly induced by postural changes, a platypnea-orthodeoxia syndrome was suspected. A transthoracic echocardiogram was performed and revealed a patent foramen ovale. A transesophageal echocardiography confirmed the presence of a significant right-to-left shunt exacerbated by the Valsalva manouver. The defect was repaired using a percutaneous transcatheter technique with complete resolution of the condition.
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Queirós et al. (2017) conducted a case report in Platypnea-Orthodeoxia Syndrome (n=1). Percutaneous transcatheter closure of patent foramen ovale was evaluated on Resolution of arterial desaturation and dyspnea. Percutaneous transcatheter closure of a patent foramen ovale completely resolved platypnea-orthodeoxia syndrome in a 65-year-old woman following a complicated cholecystectomy.
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