Key result
Pediatric echocardiography study establishes normative TAPSE and MAPSE z-scores across 1300 healthy children.
Why the study?
Reference values for TAPSE and MAPSE in healthy children aged 0-18 years were not established to guide evaluation of ventricular systolic function.
Observational (n=1,300)
No
Establishes normative reference values and z-scores for TAPSE and MAPSE in a large cohort of healthy children to guide echocardiographic assessment of ventricular function.
Supplies normative pediatric TAPSE/MAPSE values for ventricular function assessment; extends adult standards and leaves open outcome validation in diseased cohorts.
BACKGROUND: Tricuspid annular plane systolic excursion (TAPSE) and mitral annular plane systolic excursion (MAPSE) are two echocardiographic parameters which provide reliable information about the longitudinal myocardial functions of the right and left ventricles in both adult and pediatric population. The aim of this study was to determine the TAPSE and MAPSE reference values in healthy children aged 0-18 years. METHODS AND RESULTS: This prospective study included 1300 healthy children evaluated with two-dimensional echocardiography. In addition to routine echocardiographic examination, the right and left ventricular systolic functions were assessed by TAPSE and MAPSE measurements. Statistical analyses were carried out in the groups of subjects stratified according to age and body surface area. The mean and standard deviation values and z-scores of TAPSE and MAPSE were developed in each group. CONCLUSIONS: The determination of reference values for TAPSE and MAPSE in healthy children will be of guidance in the evaluation of both healthy children and those with congenital or acquired heart diseases in which the right and left ventricular systolic functions are affected. The reference values obtained will contribute to the clinical practice and the future studies.
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Keskin et al. (2020) conducted an observational in Healthy (n=1,300). Echocardiographic evaluation of TAPSE and MAPSE was evaluated on TAPSE and MAPSE reference values (mean, standard deviation, and z-scores). Echocardiographic reference values, including mean, standard deviation, and z-scores for TAPSE and MAPSE, were established in 1300 healthy children aged 0-18 years.
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