Key result
Hepatitis C infection in hemodialysis patients was associated with an increased risk of all-cause mortality (HR 1.12; 95% CI 1.05-1.20) and hepatic-related mortality (HR 5.90; 95% CI 3.67-9.50).
Why the study?
Does Hepatitis C virus infection increase the risk of mortality, hospitalization, and adverse quality of life in patients on hemodialysis?
Cohort (n=76,689)
Yes
Does Hepatitis C virus infection increase the risk of mortality, hospitalization, and adverse quality of life in patients on hemodialysis?
Hazard Ratio: 1.12 (95% CI 1.05–1.2)
HCV infection in hemodialysis patients is associated with increased mortality, hospitalization, and worse quality of life, highlighting the need for more frequent treatment.
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HCV infection was associated with higher mortality in hemodialysis patients; leaves open whether antiviral therapy improves survival.
Goodkin et al. (2016) conducted a cohort in Hepatitis C infection on hemodialysis (n=76,689). Hepatitis C virus (HCV) infection vs. HCV-negative patients was evaluated on All-cause mortality (HR 1.12, 95% CI 1.05-1.20). Hepatitis C infection in hemodialysis patients was associated with an increased risk of all-cause mortality (HR 1.12; 95% CI 1.05-1.20) and hepatic-related mortality (HR 5.90; 95% CI 3.67-9.50).
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