Key result
Lack of sleep in young adults with obesity is significantly associated with higher plasma levels of acylated ghrelin (Rho = -0.293, p = 0.028).
Why the study?
Does lack of sleep increase plasma levels of acylated ghrelin in young adults with obesity?
Cross-Sectional (n=56)
No
Does lack of sleep increase plasma levels of acylated ghrelin in young adults with obesity?
Effect estimate: Rho -0.293
p-value: p=0.028
Lack of sleep is associated with increased acylated ghrelin levels in young adults with obesity, suggesting a hormonal mechanism by which sleep deprivation may promote obesity.
Hypothesis-generating for sleep-ghrelin interactions in obese youth; prospective studies needed before any clinical application.
Interruption or lack of sleep has been linked to chronic degenerative diseases including obesity, which has tripled its figures worldwide in the last 40 years according to data from the world Health organization (WHO). Obesity associated with lack of sleep affects the Circadian rhythm which is responsible for synchronizing the energy balance during the sleep- wake cycle, hormonal secretion, homeostasis of food/energy, among the others. The aim of the study was to determine plasma levels of acylated ghrelin in obese young adults with sleep deprivation to plasma levels of acylated ghrelin in obese Young Adults. Study was carried out a total of 56 young adults with obesity, one of the groups had the condition of lack of sleep, n = 28 per group, to determine the relationship between hours of sleep levels of acylated ghrelin Spearman's correlation test was applied, a negative correlation of Rho = -0.293 and p = 0.028 was found the results obtained suggest that lack of sleep may be a factor that alters hormonal regulation and promotes obesity.
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Campos et al. (2021) conducted a cross-sectional in Obesity and sleep deprivation (n=56). Lack of sleep vs. Normal sleep (no lack of sleep) was evaluated on Correlation between hours of sleep and plasma levels of acylated ghrelin (Rho -0.293, p=0.028). Lack of sleep in young adults with obesity is significantly associated with higher plasma levels of acylated ghrelin (Rho = -0.293, p = 0.028).
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