Serum calcium levels have been measured in adult female Sprague-Dawley rats whose thyroid glands had been removed either with I131 or by surgery. The mean serum C– level of rats whose thyroids had been completely ablated with 5 μC/g body weight of I131 was within normal limits, 9.3 ± 0.02 mg 100 ml. Complete destruction of the parathyroids, as well as the thyroid gland, was effected by a dosage of 50 μC/g I131.
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Parrott et al. (1958) studied this question.