Key result
The presence of either negative T waves in leads III and V1 or peak negative T waves in V1/V2 in isolation yielded a positive predictive value of 55% and a positive likelihood ratio of 2.75, failing to meaningfully discriminate between acute pulmonary embolism and acute coronary syndrome.
Why the study?
Can specific negative T wave patterns on ECG discriminate between acute pulmonary embolism and acute coronary syndrome?
Can specific negative T wave patterns on ECG discriminate between acute pulmonary embolism and acute coronary syndrome?
Effect estimate: Positive likelihood ratio 2.75
The simultaneous presence of negative T waves in leads III and V1 along with peak negative T waves in V1/V2 on ECG strongly favors acute pulmonary embolism over acute coronary syndrome.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Rubin et al. (2021) conducted a letter in Acute pulmonary embolism and acute coronary syndrome (n=355). Isolated negative T wave patterns (Neg T in leads III and V1 or peak Neg T in V1/V2) vs. Both patterns present or neither pattern present was evaluated on Positive predictive value for acute pulmonary embolism of either ECG finding alone (Positive likelihood ratio 2.75). The presence of either negative T waves in leads III and V1 or peak negative T waves in V1/V2 in isolation yielded a positive predictive value of 55% and a positive likelihood ratio of 2.75, failing to meaningfully discriminate between acute pulmonary embolism and acute coronary syndrome.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: