Key result
Acute dyspnea with hypoxemia, normal CXR, and RV strain warrants treating as acute PE.
Case Report (n=1)
No
A clinical image challenge presenting a 72-year-old woman with acute shortness of breath, widespread T wave inversion, and elevated NT-proBNP.
A 72-year-old woman presented with sudden-onset shortness of breath. There was no associated chest pain, nausea or sweating. She had had breast cancer 14 years previously, treated by wide local excision, radiotherapy and tamoxifen. She gave no history of cardiac or pulmonary disease and had no current risk factors for venous thromboembolism. On examination she had good air entry to both lungs and normal breath sounds. Heart rate was 88/min with blood pressure 133/73 mm Hg. Her SpO2 on air was 92%–95% at rest. She had no lower limb swelling or tenderness. Revised Geneva score was 4 suggesting moderate clinical probability of pulmonary embolism. There was no suggestion of recurrent breast cancer clinically. Haemoglobin was 14.5 g/dL, renal function was normal and C-reactive protein was 9 mg/L (0–10). N-terminal pro-B-type natriuretic peptide was raised at 1158 pg/mL (0–150). Her chest X-ray (CXR) was normal and her ECG is shown below (figure 1).
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Bruce et al. (2018) conducted a case report in Acute pulmonary embolism (n=1). Dalteparin and warfarin was evaluated. Patients with acute shortness of breath, no previous cardiorespiratory disease, hypoxaemia, normal CXR and RV strain pattern on ECG should be treated as acute pulmonary embolism until proven otherwise.
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