Key result
Work stress linked to a ~3-fold higher risk of cardiovascular events.
Why the study?
Psychological stress has been identified as a risk factor for cardiovascular disease, but its association in the local setting was not established.
Does psychological stress increase the risk of cardiovascular events in patients?
Case-Control (n=227)
No
Does psychological stress increase the risk of cardiovascular events in patients?
Odds Ratio: 3.22
Absolute Event Rate: 28.2% vs 10.9%
p-value: p=<0.05
Psychological stress factors, particularly work stress and childhood abuse, are significantly associated with an increased risk of acute cardiovascular events.
May warrant stress screening in CVD prevention; hypothesis-generating pending prospective confirmation.
Introduction Stress is a phenomenon elicited in response to certain triggers that may be external or internal. Stress has been identified as a risk factor for various diseases, including cardiovascular disease. In this study, we aim to find an association between psychological stress and cardiovascular disease in the local setting Methods This case-control study was conducted in a tertiary care hospital in Pakistan from June 2019 to December 2019. One hundred and seventeen (117) patients with myocardial infarction and unstable angina were enrolled in the case group. One hundred and ten (110) patient's attendants were enrolled in the study as controlled. Results The risk of a cardiovascular event was higher in patients with a history of social isolation (OR, 2.47), marital stress (OR, 2.28), work stress (OR, 3.2), childhood abuse (OR, 2.78), or trauma (OR, 2.67). Conclusion Psychological stress is an important risk for cardiovascular disease, which is often overlooked. Efforts should be made to include questions related to psychological stress in the history-taking of patients at risk of a cardiovascular event and the management plan should include psychological counseling.
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Satyjeet et al. (2020) conducted a case-control in Cardiovascular disease (n=227). Psychological stress (e.g., work stress) vs. No psychological stress was evaluated on Cardiovascular disease (myocardial infarction or unstable angina) (OR 3.22, p=<0.05). Psychological stressors, particularly work stress (OR 3.22), childhood abuse (OR 2.78), and social isolation (OR 2.47), were significantly associated with an increased risk of cardiovascular disease.
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