Key result
Intravenous dexmedetomidine before anesthesia and during cesarean delivery was associated with lower sufentanil consumption compared to normal saline only (151.45 vs 185.42 μg, P<0.0001).
Why the study?
Does intravenous dexmedetomidine reduce sufentanil consumption in women undergoing elective cesarean delivery?
Population
392 women who received spinal anesthesia and no analgesia prior to undergoing elective cesarean delivery…
Comparison
Intravenous dexmedetomidine before anesthesia… vs Normal saline before anesthesia and during…
Design
Cohort
Follow-up
Hospitalization period
Authors
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May reduce sufentanil use before elective cesarean; leaves open need for randomized confirmation before practice change.
Cohort (n=392)
No
Does intravenous dexmedetomidine reduce sufentanil consumption in women undergoing elective cesarean delivery?
Absolute Event Rate: 151.45% vs 185.42%
p-value: p=<0.0001
Intravenous dexmedetomidine administered before spinal anesthesia for elective cesarean delivery reduces postoperative sufentanil and ondansetron consumption and shortens hospital stay.
Wei et al. (2020) conducted a cohort in Elective cesarean delivery (n=392). Dexmedetomidine before anesthesia and during delivery vs. Normal saline before anesthesia and during delivery (with or without dexmedetomidine after delivery) was evaluated on Sufentanil consumption during hospitalization (p=<0.0001). Intravenous dexmedetomidine before anesthesia and during cesarean delivery was associated with lower sufentanil consumption compared to normal saline only (151.45 vs 185.42 μg, P<0.0001).
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