Jietacins A and B, new nematocidal antibiotics from a stretomyces sp. Taxonomy, isolation, and physico-chemical and biological properties.

Jietacins A and B, newazoxy antibiotics, were isolated from the culture broth of a streptomycete.The antibiotics have the molecular formulae of Ci8H34N2O2 and Ci9H36N2O2, respectively.Both possess an azoxy group.They have potent activity against the pine wood nematode, Bursaphelenchus lignicolus, and are weakly active against some fungi.In the course of our screening program for new nematocidal antibiotics from soil microorganisms, new antibiotics named jietacins A and B were isolated from the culture broth of an actinomycete strain KP-197 which was isolated from a soil sample collected at Jietai Temple in Beijing, Peoples Republic of China.The present paper deals with taxonomy of the producing strain, fermentation, isolation, and physico-chemical and biological properties ofjietacins A and B.