Key result
Numerical solutions of three-dimensional Navier-Stokes equations accurately determined the shape of the separating surface in microvascular bifurcations, agreeing with experimental data.
This computational model accurately predicts the shape of the separating surface in microvascular bifurcations, which can be used to predict downstream blood constituent concentrations.
Validates 3D Navier-Stokes modeling of microvascular separation; leaves open clinical hemodynamic translation.
The shape of the separating surface formed by the streamlines entering the branches of microvascular bifurcations plays a major role in determining the distribution of red blood cells and other blood constituents downstream from the bifurcation. Using the finite element method, we determined the shape of the surface through numerical solution of three dimensional Navier-Stokes equations for fluid flow at low Reynolds numbers in a T-type bifurcation of circular tubes. Calculations were done for a wide range of daughter branch to parent vessel diameter ratios and flow ratios. The effect of Reynolds number was also studied. Our numerical results are in good agreement with previously reported experimental data of Rong and Carr (Microvascular Research, Vol. 39, pp. 186-202, 1990). The numerical results of this study will be used to predict the concentration of blood constituents downstream from microvascular bifurcations providing that the inlet concentration profile is known.
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Enden et al. (1992) studied this question. Numerical solution of three dimensional Navier-Stokes equations was evaluated on Shape of the separating surface formed by streamlines entering branches of microvascular bifurcations. Numerical solutions of three-dimensional Navier-Stokes equations accurately determined the shape of the separating surface in microvascular bifurcations, agreeing with experimental data.
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