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September 23, 2026Cardiovascular UltrasoundOpen Access

Surgical excision of rare cystic cardiac myxoma yields complete resolution without recurrence at one year.

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Why the study?

Cystic myxoma is a rare variant of cardiac myxoma with few cases reported, and its unique anatomical and hemodynamic features are not well described.

Population

54-year-old woman with exertional dyspnea, chest tightness, and intermittent dizziness

Design

Case report

Key result

Surgical excision of a rare balloon-like cystic cardiac myxoma resulted in complete resolution of the mass and normal mitral valve function, with no tumor recurrence at one-year follow-up.

Authors

XZXiaofang ZhongSLShuyu LuoLCLixin Chen

Discussion

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Overview

Supports surgical excision for rare cystic myxomas; hypothesis-generating for multimodality imaging and long-term outcomes.

Key Points

  • To describe the clinical presentation, hemodynamic characteristics, and surgical findings of a rare balloon-like cystic cardiac myxoma mimicking a blood-filled cyst.
  • Evaluated a 54-year-old woman presenting with exertional dyspnea, chest tightness, and dizziness using ECG, laboratory testing, transthoracic echocardiography, contrast echocardiography, and transesophageal echocardiography.
  • Performed surgical resection with intraoperative verification of lesion flow dynamics using cardioplegic solution delivery.
  • Echocardiography revealed a balloon-like cystic mass in the left atrium with iso-myocardial contrast enhancement mimicking a blood-filled cyst.
  • Transesophageal echocardiography and intraoperative cardioplegia administration confirmed a distinct arterial inflow at the cyst base and an outflow orifice, leading to successful tumor resection.

Study Design

Type

Case Report (n=1)

Multicenter

No

Structured PICO

P
Population
A 54-year-old woman presenting with exertional dyspnea and chest tightness who was diagnosed with a rare balloon-like cystic cardiac myxoma.
I
Intervention
Surgical resection
O
Outcome
Successful resection and histopathological confirmation

This case highlights a rare balloon-like cystic variant of cardiac myxoma that mimics a blood-filled cyst, demonstrating the utility of multimodality echocardiography in its diagnosis.

Limitations

  • Absence of cardiac magnetic resonance (CMR) imaging for further tissue characterization and preoperative evaluation.

Cite This Study

Zhong et al. (2026) conducted a case report in Cystic cardiac myxoma (n=1). Surgical excision was evaluated on Tumor recurrence and resolution of symptoms. Surgical excision of a rare balloon-like cystic cardiac myxoma resulted in complete resolution of the mass and normal mitral valve function, with no tumor recurrence at one-year follow-up.

synapsesocial.com/papers/6ab39dc64f6cc12e38b515e7https://doi.org/10.1186/s12947-026-00376-4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cystic cardiac myxoma: a rare variant of cardiac myxoma in a woman with acute stroke2024 · 1 citations
  2. 2Case Report: Giant left atrial cystic tumor: myxoma or intracardiac blood cyst?2024 · 1 citations
  3. 3Cardiac myxoma with cartilaginous differentiation-An uncommon variant presented as mitral stenosis2019 · 5 citations
  4. 4A rare left ventricular cardiac myxoma mimicking fibroma2022 · 4 citations
  5. 5Atrial myxoma—the Great Masquerader2019 · 4 citations