Key result
Novel imaging modalities enhance vulnerable plaque detection to help prevent acute coronary syndromes.
Why the study?
Atherosclerotic plaques prone to rupture are implicated in ACS pathogenesis, but non-invasive methods for primary prevention remain under study.
This review highlights the ongoing transition of vulnerable plaque detection technologies from basic research to clinical practice, emphasizing the need for non-invasive imaging in primary prevention.
Advances vulnerable plaque imaging research; leaves open whether detection improves ACS prevention in practice.
Coronary heart disease is the commonest cause of death in Western countries, and atherosclerotic plaques that are prone to rupture have been implicated in the pathogenesis of acute coronary syndromes (ACS). Intensive research has been directed at plaque detection, and various invasive methods have been developed thus far that fulfill this purpose and a lot of them are being applied in the clinical setting. Since invasive methods cannot be used for primary prevention, non-invasive imaging modalities are being studied to enhance the diagnostic armory of clinicians in their difficult task of detecting and preventing ACS.
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Toutouzas et al. (2012) conducted a review in Coronary heart disease and acute coronary syndromes. Invasive and non-invasive plaque detection methods was evaluated. Invasive and non-invasive imaging modalities are being developed and studied to enhance the detection of vulnerable atherosclerotic plaques and prevent acute coronary syndromes.
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