Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 15, 2016Journal of Radiation Research and Applied SciencesOpen Access

Evaluation of low dose ionizing radiation effect on some blood components in animal model

View Full Paper
Ask AI
Bookmark
Share

Key result

Low dose ionizing radiation caused a significant, dose-dependent reduction in white blood cell counts starting at 0.3 Gy compared to the control group.

Why the study?

Does low dose ionizing radiation affect blood components in an animal model?

Population

110 animal rats divided into 8 groups

Comparison

Low dose ionizing radiation at various dose levels vs Control group (unirradiated)

Design

Preclinical

Authors

HEH. El-ShanshouryGEG. El-ShanshouryAAA AbazaNuclear Materials Authority

Discussion

Loading...

Member takes

Implication

May signal hematologic risks from low-dose radiation; hypothesis-generating for human biodosimetry, with no practice change warranted.

Structured PICO

Does low dose ionizing radiation affect blood components in an animal model?

P
Population
110 animal rats divided into 8 groups evaluated for hematological parameters pre- and post-irradiation.
E
Exposure
Low dose ionizing radiation (IR) at various dose levels (e.g., 0.3 Gy to 1 Gy)
C
Comparator
Control group (unirradiated)
O
Outcome
Hematological parameters (WBC, Platelet, and RBC counts) pre- and post-irradiationsurrogate

Low dose ionizing radiation causes a significant, dose-dependent reduction in blood cell counts in an animal model, highlighting potential health risks and the need for biodosimetry protocols.

Cite This Study

El-Shanshoury et al. (2016) studied Exposure to low dose ionizing radiation (n=110). Low dose ionizing radiation vs. Control group was evaluated on Hematological parameters (WBC, Platelet, and RBC counts). Low dose ionizing radiation caused a significant, dose-dependent reduction in white blood cell counts starting at 0.3 Gy compared to the control group.

synapsesocial.com/papers/6ab477c836ef184be74dd568https://doi.org/10.1016/j.jrras.2016.01.001
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevention of Gamma Radiation Induced Anaemia in Mice by Diltiazem2004 · 37 citations
  2. 2Effects of Proton Radiation Dose, Dose Rate and Dose Fractionation on Hematopoietic Cells in Mice2010 · 40 citations
  3. 3Kinetics of Neutrophils in Mice Exposed to Radiation and/or Granulocyte Colony-Stimulating Factor Treatment2013 · 38 citations