Screening of Botanical Drugs against Lassa Virus Entry

This is the authors' abstract. We don't add key points for this paper.

Currently, there is no approved therapy to treat Lassa fever (LASF). Our goal was to identify potential candidate molecules for LASF therapy. Herein, we screened a botanical drug library and identified two compounds, casticin and bergamottin, that inhibited LASV entry via different mechanisms.