Case report demonstrates successful transurethral resection of an incidental bladder paraganglioma, suggesting endoscopic management is feasible for small favorable tumors.
Bladder paraganglioma is a rare neuroendocrine tumor (<0.5% of bladder neoplasms) that may be discovered incidentally or present with catecholamine-related symptoms. A 69-year-old man under oncologic surveillance for a renal cell carcinoma showed a bladder wall lesion enlarging from 4 × 5 mm to 8 × 6 mm over two years on CT. Cystoscopy demonstrated a small sessile lesion with intact mucosa. Complete transurethral resection was performed with continuous hemodynamic monitoring. Histology confirmed paraganglioma with synaptophysin and chromogranin A positivity, Ki-67 < 5%, and preserved SDHA/SDHB. Postoperative ¹⁸F-FDOPA PET/CT showed no residual or metastatic disease. Selected small incidental tumors with favorable pathology may be effectively managed by complete transurethral resection.
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Ahmed et al. (2026) studied this question.
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