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In a group of patients suffering from rheumatoid arthritis, 10 were found who had taken 5.0 mg of prednisolone every day at 10 pm for from 100 to 180 weeks. Pituitaryadrenocortical reserve, as judged by the methopyrapone test, was studied in these 10. In all of them some reserve was observed to be present.
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John R. Andrade (1964) studied this question.
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