Key result
Long-duration exercise cardiac rehab linked to ~49% lower mortality vs non-participation in CHD.
Why the study?
Evidence for long-term health effects of exercise-based cardiac rehabilitation is scarce and rare in health care service research.
Does exercise-based phase III cardiac rehabilitation reduce mortality and loss of working capacity in patients with coronary heart disease?
Cohort (n=54,163)
Does exercise-based phase III cardiac rehabilitation reduce mortality and loss of working capacity in patients with coronary heart disease?
Hazard Ratio: 1.97 (95% CI 1.6–2.43)
p-value: p=<0.0001
Participation in exercise-based phase III cardiac rehabilitation is independently associated with significantly reduced mortality and loss of working capacity in patients with coronary heart disease.
Prioritizes cardiac rehabilitation enrollment in coronary heart disease; reinforces mortality benefit with longer programs.
BACKGROUND: Exercise-based cardiac rehabilitation is safe and implemented in international cardiac rehabilitation guidelines. Evidence for long-term health effects is scarce and rare for health care service research. OBJECTIVE: The aim of this study is to evaluate the effectiveness of exercise-based phase III cardiac rehabilitation programs in improving mortality and working capacity outcomes. METHODS: The present analyses used claims data of the German pension fund from 2010 to 2017. Overall, 54,163 patients with coronary heart disease (ICD10 I20.-I25.) were included and followed up for exercise-based cardiac rehabilitation participation (mean 4.3 ± 1.9 years). All patients were categorized according to participation duration (long: ≥ 90 days, short: < 90 days, no). The effectiveness of exercise-based rehabilitation was analyzed by calculating adjusted hazard ratios for mortality and reduced working capacity in relation to program participation. RESULTS: Of all the cardiac patients, 57.6% received medical recommendations for exercise-based phase III rehabilitation, and 16.8% participated in this rehabilitation. In total, 1776 (3.3%) patients died during the study period, and 3050 (5.5%) received reduced earning capacity pensions. Mortality risk was nearly doubled for those who did not participate in exercise-based cardiac rehabilitation compared to those who participated for a long duration (HR 1.97, 95% CI 1.60-2.43) and 44% higher compared to a short participation (HR 1.44, 95% CI 1.03-2.01). Furthermore, the risk of reduced working capacity was higher for those who did not participate compared to those who participated for a short duration (HR 1.24, 95% CI 1.00-1.54). CONCLUSION: Exercise-based phase III cardiac rehabilitation is independently associated with reduced mortality and reduced loss in working capacity. Strong efforts should be made to increase participation rates to improve cardiac patients care.
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Gabrys et al. (2021) conducted a cohort in Coronary heart disease (n=54,163). No participation in exercise-based phase III cardiac rehabilitation vs. Long participation (≥ 90 days) in exercise-based phase III cardiac rehabilitation was evaluated on Mortality (HR 1.97, 95% CI 1.60-2.43, p=<0.0001). Patients with coronary heart disease who did not participate in exercise-based cardiac rehabilitation had a nearly doubled mortality risk compared to those who participated for a long duration (HR 1.97).
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