Key result
Class III antiarrhythmics linked to higher sinus rhythm maintenance after electrical cardioversion.
Why the study?
Long term success rates and factors influencing persistence of sinus rhythm after a first electrical cardioversion for atrial fibrillation are not well defined.
What clinical, functional, and pharmacological factors predict the maintenance of sinus rhythm after a first electrical cardioversion for atrial fibrillation?
Population
85 patients undergoing first electrical cardioversion for atrial fibrillation
Comparison
Clinical, functional, and pharmacological variables including class III antiarrhythmic drugs
Design
Retrospective observational study with univariate and multivariate analysis
Follow-up
At least 100 days
Authors
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Analysis of predictors after cardioversion for longstanding AF; leaves open whether targeted strategies improve sinus rhythm maintenance.
Observational (n=85)
What clinical, functional, and pharmacological factors predict the maintenance of sinus rhythm after a first electrical cardioversion for atrial fibrillation?
p-value: p=<0.03
Class III antiarrhythmic drugs, shorter duration of preceding atrial fibrillation, and younger age are key determinants of long-term sinus rhythm maintenance after first electrical cardioversion, whereas echocardiographic parameters are not.
Duytschaever et al. (1998) conducted an observational in Atrial fibrillation (n=85). Class III antiarrhythmic drugs, duration of atrial fibrillation, and age was evaluated on Maintenance of sinus rhythm at 100 days (p=<0.03). Class III antiarrhythmic drugs (p<0.01 and p<0.02), duration of atrial fibrillation (p<0.03), and age <75 years predicted long-term sinus rhythm maintenance after first electrical cardioversion.
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