Key result
Renal insufficiency links to worse post-EVAR outcomes, while diabetes shows lower risk than expected.
Why the study?
The effects of diabetes mellitus and renal insufficiency on outcomes following endovascular abdominal aneurysm repair were not well defined, particularly after adjusting for confounders.
Do diabetes mellitus and renal insufficiency impact outcomes following endovascular abdominal aortic aneurysm repair?
Observational (n=12,451)
Do diabetes mellitus and renal insufficiency impact outcomes following endovascular abdominal aortic aneurysm repair?
Renal insufficiency significantly worsens outcomes after EVAR, warranting a conservative approach, whereas diabetes mellitus confers less risk than previously thought, making EVAR a favorable option for diabetic patients.
Answers are grounded in this paper and cite their sources.
May support renal risk stratification before EVAR; extends observations on diabetes but remains hypothesis-generating.
The purpose of this study was to determine the effects of diabetes mellitus (DM) and renal insufficiency (RI) on outcomes following endovascular abdominal aneurysms repair (EVAR). The surgical outcomes associated with endovascular repair in 12 451 patients are reported. After adjusting for confounders, DM and RI were analyzed against the primary outcome variables of mortality, major complications, length of stay, treatment cost, and routine discharge rates. This study shows that RI has a greater negative influence on the outcome of EVAR than previously suspected and that a conservative approach to the use of EVAR in patients with RI is warranted. While DM has negative impact on outcomes following open repair of abdominal aortic aneurysms, this study shows that it may confer less of a risk than previously thought, when confounders are controlled for, and that EVAR might be a favorable treatment modality for patients with abdominal aortic aneurysm and coexisting DM.
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Markovic et al. (2010) conducted an observational in Abdominal aortic aneurysm (n=12,451). Diabetes mellitus and renal insufficiency was evaluated on Mortality, major complications, length of stay, treatment cost, and routine discharge rates. Renal insufficiency negatively impacted outcomes following endovascular abdominal aortic aneurysm repair, whereas diabetes mellitus conferred less risk than previously thought.
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