Key result
The GH4.1c and GH6.2a alleles in the bovine growth hormone gene were associated with higher milk yield (+/-300 kg per lactation), fat (+/-8 kg), and protein (+/-7 kg) in Holstein bulls.
Population
128 Holstein bulls
Comparison
Sequence variations in the bovine growth hormone… vs Different alleles of the GH gene
Design
Preclinical
Authors
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Supports marker-assisted selection in Holstein cattle; leaves open functional validation and economic impact.
Observational (n=128)
Effect estimate: +/-300 kg
p-value: p=<=0.005
Specific polymorphisms in the bovine growth hormone gene (GH4.1c and GH6.2a) are positively associated with increased milk yield, fat, and protein content in Holstein cattle.
Yao et al. (1996) conducted an observational in Milk production traits (n=128). GH4.1c and GH6.2a alleles vs. GH4.1t and non-GH6.2a alleles was evaluated on Milk yield (+/-300 kg, p=<=0.005). The GH4.1c and GH6.2a alleles in the bovine growth hormone gene were associated with higher milk yield (+/-300 kg per lactation), fat (+/-8 kg), and protein (+/-7 kg) in Holstein bulls.
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