Key result
APEX implantable BP sensor matches Millar catheters with no acute thrombus formation in calves.
Why the study?
An implantable blood pressure sensor suitable for long-term use with LVADs was needed to provide accurate and stable pressure measurements.
Does the APEX implantable blood pressure sensor accurately measure blood pressure and resist thrombus formation compared to Millar catheters in an LVAD model?
Population
3 sensors for bench testing and 5 ventricular assist acute calf experiments
Comparison
APEX implantable flow-through blood pressure sensor prototype vs Millar pressure catheter sensors
Design
Preclinical study with bench testing and acute animal experiments
Follow-up
193 days for long-term drift bench testing; acute for calf experiments
Authors
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Prototype enables integrated LVAD pressure sensing in bench tests; leaves open in vivo validation and durability before clinical use.
Does the APEX implantable blood pressure sensor accurately measure blood pressure and resist thrombus formation compared to Millar catheters in an LVAD model?
A novel implantable flow-through blood pressure sensor for LVADs demonstrates accurate pressure measurement, long-term stability, and resistance to thrombus formation in preclinical testing.
Bullister et al. (2001) studied Ventricular assist device monitoring (n=5). APEX pressure sensor vs. Millar pressure catheter sensors was evaluated on Pressure output comparisons and thrombus formation. The APEX implantable blood pressure sensor showed similar pressure tracings to Millar catheters in 5 acute calf experiments, with no visible evidence of thrombus formation.
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