Key result
Individual differences in behavioral responses to palatable food and lesser sucrose intake suppression in response to CCK predicted greater weight gain in rats on a high-fat/high-sugar diet.
Population
Outbred chow-maintained Sprague-Dawley rats
Design
Preclinical
Follow-up
5 weeks
Authors
Loading...
May identify obesity-prone phenotypes via behavior and CCK responses in rats; hypothesis-generating for human translation.
Individual differences in behavioral responses to palatable food and CCK predict susceptibility to diet-induced obesity in a rat model.
Wald et al. (2019) studied Diet-induced obesity. Behavioral responses to palatable food and CCK was evaluated on Weight gain after 5 weeks of HFHSD maintenance. Individual differences in behavioral responses to palatable food and lesser sucrose intake suppression in response to CCK predicted greater weight gain in rats on a high-fat/high-sugar diet.