Demonstration of γ-trace in normal endocrine cells of the adrenal medulla and in phaeochromocytoma

gamma-Trace was demonstrated by the immunohistochemical peroxidase/anti-peroxidase technique to occur in normal chromaffin cells of the adrenal medulla from African green monkey, capuchin monkey and beagle dog and in the cells of a norepinephrine-producing human phaeochromocytoma. The presence of gamma-trace in the endocrine epithelial cells of the adrenal medulla suggests that gamma-trace might be related to the neuroendocrine system.