Key result
Steroid-antiviral combination therapy was more effective than steroid-only treatment for continuous improvement after 6 weeks in patients with zoster sine herpete and accompanying pain (P<0.05).
Why the study?
Does steroid-antiviral combination therapy improve recovery in patients with zoster sine herpete causing facial palsy compared to steroid-only treatment?
Population
45 patients with zoster sine herpete (ZSH) causing facial palsy
Comparison
Steroid-antiviral combination therapy vs Steroid-only treatment
Design
Cohort
Follow-up
up to 6 weeks
Authors
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May support antiviral addition for painful ZSH palsy; leaves open need for RCTs before changing practice.
Cohort (n=45)
Does steroid-antiviral combination therapy improve recovery in patients with zoster sine herpete causing facial palsy compared to steroid-only treatment?
p-value: p=< .05
Steroid-antiviral combination therapy is more effective than steroid-only treatment for facial palsy caused by zoster sine herpete, particularly in patients with accompanying pain.
Lee et al. (2012) conducted a cohort in Zoster sine herpete causing facial palsy (n=45). Steroid-antiviral combination therapy vs. Steroid-only treatment was evaluated on Continuous improvement after 6 weeks (p=< .05). Steroid-antiviral combination therapy was more effective than steroid-only treatment for continuous improvement after 6 weeks in patients with zoster sine herpete and accompanying pain (P<0.05).
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